1950_busch_1464_1.pdf

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VI LSD No o_
BUSCH, AoK._ JOHNSON_ WoCo
(St.Louis State Hospital_ Washington
_D
as an aid in psychotherapy.
Dis_ nerv. System
I_OBLEM:
Use of LSD to induce
UnivoMedoSchool_
Missouri)
lll., (1950).
241
a transitory
delirious
state°
JTHOD
& DOSAGE: Ave.rage effective dose for women 0o5 c_, (30 gamma)
and for men 2 cc (40 gamma)o Pats° aware of drug activity within
�½ - l�½ hours° Maximum effectiveness from2
- 2_ hours. Effect
persisted for as long as 8 hours though 4 hours appeared to be
the usual length of action°
MATERIAL: 21 psychotic women and subsequently
psychotherapy
(2 males_ 6 females)°
B_SULTS"
l) P_sychotic patientso
8 pats° undergoing
a) Mental effects° Excitation, increase in activity and greater
ver_I
expressiS_
of psychopathology°
Occasional
short periods
of _onfusion and disorientation
and occasional transitory visual
of
hallucinations
o
Most pats. exhibited some euphoria°
_,,Tab_e
_ _
behaviour, symptoms of pats° under LSD)o
b) _Systemic effects° (In order of frequency) gastric distress_
,_
_--
nausea_ o_,_aslonal _voml°to
Ing_ muscle irritability_
developing
i÷
n;o tremors and sometimes twitching_ dizziness_ dilation of
p_.,.J
...... _ <;hilliness_
increase
in pulse
rater
occasionally
head_
a,,,,,__ a few cases periodic flushing of the skin° No changes
i:_
observed in b_.ood pi_ture
urine
NPN or blood sugar. No .con_,_
slstent
ch_ages in B.Po and temperature.
2)
P_&t_ents _m_der_oir_osychotheraoyo
E,_fe_°ot...
.,,,
,
..,_,_ was a transitory toxic state disturbing barr_er
LSD
'_
of repression and. permitting re-examination
of signifie_'_t
experiences of the past_ which were sometimes relived with
Ir_ghtenm.ag realmsm. Some pats. then able _o re-evaluate
emo,.._o.o.a._
meaning of their symptoms and were improved. Most
were bette_ o able to, organize their ideaso 2 patso _mp_-__i
_-"_,'_
suffi_ientl_
to discontinue
treatment
(Table giving _ .....
_
of
LSD treatmen%)
.F_ILU_S 0"._z,
group I_ 3 manlcs and 4 paranoid s,_.hmz_p_n.e,
........
required hydrotherapy be,:_auseof excessive increase in activity°
.SIDE-EFFECTS_
see Results
§ I bo
SUMMARY_ Effect of LSD studied in 2i psychotic pats° After obtain ....
ing good results_ LSD used in 8 pats. _ undergoing
psy_ho therapy ,,,
az_d most were improved. 2 improved sufficiently to discontinue
treatment.
COMMENT_ Author observed that LSD permits
recall of experiences
provoking az_xiety and fear without causing sluggishness
of spee_h
as
does
_'_'_'÷'°_'
or marked confusion produced during IST and
_.
_
_
£cilow ....
ing ECTo He believes that LSD may enable psychotherapy to be
sh,_z_.ened.This is questionable° It is more probable that _o;
may find the place in experimentally
induced psychoses_ al,_hoagh
mes_aline is at present a drug most frequently used.
INDICATIONS
VI LSD
NKT/bh
•
in _M 398
3_0
%-
Psychoses
Psychotherapy
351 _>_

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