1956_apter_4278_1.pdf

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LSD No.402 (§ 102a)
0
52
retina
M 377 psychotic
effect
_,
J.T., PFEIFFER, CoCo (Manteno State Hospo, Manteno,
Zninois_
Deptoof Pharmacolo, Emory Univ. School of Medo, Atl-
_,
Georgia)
_ect
of hallucinogenic
drugs on the electroretinogram.
-
Amer.J.Ophthalmo 4__29
206 (1956, No. 4/II)o
Similar report to that of APTER & PFEIFFER, LSD No.
305.
In
the discussion the following remarks are of interest'_
_TTS__ The dose of LSD used in this study is a whole order of
r_gnitude greater than that used in humamso The usual
hallucinogenic dose in humans is close to 1/50 of the amount
um@d in the present experiments.
_L_
A few
experiments
were made in rabbits with serotonin
and
lysergic acid _LSD?J to see whether these drugs interfered
with the electrically measured function of the pigment epithel-
ium. The experiments had negative results. The electroretinogram
wmm not specifically altered_ and the D.Co potential across the
eye
and the response to azide were not appreciably
changed.
JAC_BSON_ A study has been made in one human but unfortunatel_
he
did
not have hallucinations. One human was given 50 mg_g_
LSD. His spontaneous reactions and his reaction to light stim_
ull were recorded for two hours. It was impossible to judge
outcome from his spontaneous activity and there was no
Offect on reactions to light stimuli.
(E_et
_rt
d'agents hallucinog_nes
sur l' 4lectror4tinogramme)
similaire _ celui d'APTER & PFEIFFER, LSD No 505, Rapport
_1_r°Bs/RI
i157 @%

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